Dead Space Calculation
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This is given as a ratio of dead space to tidal volume.
Dead space calculation. The recent article by tusman et al. Medical software clinical software medical systems medical calculators clinical calculators medical information processing practice guidelines clinical. Inspired air is brought to body temperature increasing the affinity of hemoglobin for oxygen improving o 2 uptake.
Particulate matter is trapped on the mucus that lines the conducting airways allowing its. Va paco2 vt ptco2 vdpdco2 where ptco2 is the partial pressure of mixed expired air and pdco2 is the partial pressure of dead space air aka that of normal atmospheric air. Dead space ventilation the portion of a tidal volume that does not contribute to gas exchange was first described and calculated by the bohr equation in 1891 1 and later by the enghoff modification of the bohr equation in 1938.
Anatomical dead space in cubic centimetres roughly equalled a subject s ibw in pounds difference between measurements made at different end inspiratory lung volumes avg 100 cm3difference in dead space between the largest and smallest starting volumes measured dead space would decrease if a 20 s breath hold preceded the exhalation. 1 uses mass balance equations to apportion ventilation as if it were divided between a single perfused alveolar compartment and a dead space compartment. The model is quantified by the christian bohr equation v d v t 1 p ē co 2 paco 2.
Physiological dead space total dead space conducting airways anatomic dead space pulmonary capillaries alveolar dead space. The bohr equation named after danish physician christian bohr 1855 1911 describes the amount of physiological dead space in a person s lungs. 2 physiologic dead space fraction dead space divided by tidal volume v d v t as defined by bohr and enghoff is the sum of anatomic or airway dead space v d anat and alveolar dead space v d alv divided by the v t.
Va paco2 vt ptco2 vd 0 va paco2 vt ptco2.
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